Episodes
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Generic Name Fentanyl
Trade Name Sublimaze
Indication Supplement to general anesthesia, continuous IV infusion for purpose of analgesia
Action Binds to opiate receptors in CNS altering perception of pain, producing CNS
depression
Therapeutic Class Opioid Analgesic
Pharmacologic Class Opioid agonists
Nursing Considerations • Use caution with increased ICP, head trauma, adrenal insufficiency
• Avoid...
Published 06/28/23
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Generic Name Famotidine
Trade Name Pepcid
Indication Short term treatment of active ulcer, GERD, treatment of heartburn, indigestion,
management of Zollinger Ellison syndrome, prevention of GI bleeding in critically
ill patients, management of symptoms associated with overuse of NSAIDs
Action Blocks action of histamine located in gastric parietal cells, inhibits gastric acid
secretion
Therapeutic...
Published 06/26/23
Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Escitalopram
Trade Name Lexapro
Indication Major depressive disorder, anxiety disorder, PCD, PTSD, social phobia
Action Increases the extracellular levels of serotonin in the synaptic cleft by selectively
inhibiting its reuptake
Therapeutic Class Antidepressant
Pharmacologic Class SSRI
Nursing Considerations • Contraindicated with MAOI
• May cause suicidal thoughts, insomnia, drowsiness,...
Published 06/23/23
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Generic Name Erythromycin
Trade Name E-Mycin
Indication Useful in place of penicillin when patient cannot take penicillin, upper and lower
respiratory tract infections, otitis media, skin infections, pertussis, syphilis,
rheumatic fever
Action Bacteriostatic: suppresses bacterial protein synthesis
Therapeutic Class Anti-infective
Pharmacologic Class Macrolide
Nursing Considerations • Causes QT...
Published 06/21/23
Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Epoetin
Trade Name Epogen
Indication Anemia
Action Stimulates erythropoiesis (production of RBCs)
Therapeutic Class Antianemic
Pharmacologic Class Hormones
Nursing Considerations Assess dialysis shunts Contraindicated in albumin hypersensitivity May cause Seizures CHF MI CVA Hypertension Do not shake vial Initiate seizure precautions Monitor Bleeding times Signs of anemia
Published 06/19/23
Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Epinephrine
Trade Name Adrenalin, EpiPen
Indication Asthma and COPD exacerbations, allergic reactions, cardiac arrest, anesthesia adjunct
Action Affects both beta1 and beta2 also has alpha agonist properties resulting in bron-
chodilation and increases in HR and BP. Inhibits hypersensitivity reactions.
Therapeutic Class Antiasthmatic, bronchodilator, vasopressor
Pharmacologic Class...
Published 06/16/23
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Generic Name Enoxaparin
Trade Name Lovenox
Indication Prevention of VTE, DVT, and PE
Action Prevents thrombus formation by potentiating the inhibitory effect of antithrom-
bin on factor Xa and thrombin. Enoxaparin is a low molecular weight heparin.
Therapeutic Class Anticoagulant
Pharmacologic Class Antithrombotic
Nursing Considerations • Contraindicated in pork hypersensitivity
• Monitor for signs...
Published 06/14/23
Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Enalapril
Trade Name Vasotec
Indication hypertension, management of CHF
Action Block conversion of angiotensin I to angiotensin II, increases renin levels and
decreases aldosterone leading to vasodilation
Therapeutic Class Antihypertensives
Pharmacologic Class ACE Inhibitor
Nursing Considerations • May cause hypersensitivity (allergic) reactions and angioedema (swelling of face, lips,...
Published 06/12/23
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Generic Name dopamine
Trade Name Inotropin
What is the indication for Dopamine? used to improve blood pressure, cardiac output, and urine output
Action Smaller doses result in renal vasodilation
Doses 2-10mcg/kg/min result in cardiac stimulation by acting on beta1 receptors
Doses >10mcg/kg/min stimulate alpha receptors leading to vasoconstriction (↑SVR)
What is the therapeutic class for Dopamine?...
Published 06/09/23
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Generic Name Dobutamine
Trade Name Dobutrex
Indication Short term management of heart failure
Action Dobutamine has a positive inotropic effect (increases cardiac output) with very
little effect on heart rate. Stimulates Beta1 receptors in the heart.
Therapeutic Class Inotropic
Pharmacologic Class Beta-adrenergic agonist
Nursing Considerations • Monitor hemodynamics: hypertension, ↑HR, PVCs
• Skin...
Published 06/07/23
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Generic Name Divalproex
Trade Name Depakote
Indication Seizures, manic episodes, prevention of headache
Action Increases the level of GABA (inhibitory neurotransmitter) in CNS
Therapeutic Class Anticonvulsant, vascular headache suppressants
Pharmacologic Class None
Nursing Considerations • May cause suicidal thoughts, agitation, dizziness, insomnia, hepatotoxicity,
pancreatitis
• Increases risk for...
Published 06/05/23
Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Diphenoxylate/atropine
Trade Name Lomotil
Indication Treatment for diarrhea
Action Inhibits GI motility via anticholinergic effects
Therapeutic Class Antidiarrheal
Pharmacologic Class Anticholinergic
Nursing Considerations • Contraindicated with angle-closure glaucoma, dehydration
• Structurally related to opioids so use caution with patients that have allergies to opioids
• May cause...
Published 06/02/23
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Generic Name Diphenhydramine
Trade Name Benadryl
Indication Allergy, anaphylaxis, sedation, motion sickness, antitussive
Action Antagonizes effects of histamine, CNS depression
Therapeutic Class Allergy, cold and cough remedy, antihistamine, antitussive
Pharmacologic Class Antihistamine
Nursing Considerations • May cause drowsiness, anorexia, dry mouth, nausea, chest tightness, thick
secretions,...
Published 05/31/23
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Generic Name Diltiazem
Trade Name Cardizem
Indication Hypertension, angina, SVT, AFib, aflutter
Action Inhibits calcium transport resulting in inhibition of excitation and contraction,
leads to depression of AV and SA node leading to decreased HR, leads to vasodi-
latation and decreased blood pressure.
Therapeutic Class Antianginals, antiarrhythmics, antihypertensive
Pharmacologic Class Ca Channel...
Published 05/29/23
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Generic Name Digoxin
Trade Name Lanoxin
Indication CHF, AFib, A-flutter
Action Positive inotropic effect (increases force of myocardial contraction), prolongs
refractory period, ↓ conduction through SA and AV nodes. Essentially digoxin is
given to increase cardiac output and slow the rate.
Therapeutic Class Antiarrhythmic, inotropics
Pharmacologic Class Digitalis glycosides
Nursing Considerations •...
Published 05/26/23
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Generic Name Diazepam
Trade Name Valium
Indication Anxiety, pre-op sedation, conscious sedation, treatment of seizures, insomnia,
management of alcohol withdrawal
Action Decreases the effects of voltage gated sodium channels to depresses the CNS
Therapeutic Class Antianxiety agents, anticonvulsants, sedative/hypnotics, skeletal muscle relax-
ants (centrally acting)
Pharmacologic Class Benzodiazepine
...
Published 05/24/23
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Generic Name Dexamethasone
Trade Name Decadron
Indication Manage cerebral edema, assess for Cushing’s Disease
Action Suppress inflammation and normal immune response. Used in inflammatory states
to decrease inflammation.
Therapeutic Class Antiasthmatics, corticosteroids
Pharmacologic Class Corticosteroids
Nursing Considerations • Excreted by the liver – monitor liver profile
• Avoid in active...
Published 05/22/23
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Published 05/19/23
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Generic Name Cyclosporine
Trade Name Sandimmune
Indication Prevention of rejection in transplantation, treatment of severe RA, management
of ulcerative colitis
Action Inhibits normal immune response primarily by decreasing the activity of T cells
Therapeutic Class Immunosuppressant, antirheumatics (DMARD)
Pharmacologic Class Polypeptides (cyclic)
Nursing Considerations • May cause seizures, tremors,...
Published 05/19/23
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Generic Name Cortisone
Trade Name Cortone
Indication Management of adrenocortical insufficiency (Addison’s Disease). Replace cortisol
in states of deficiency, suppress inflammation and normal immune response.
Action The adrenal glands sit on top of the kidneys.
The adrenal glands excrete steroid hormones, including cortisol that play a role in
increasing blood sugars, immune suppression, and metabolism...
Published 05/17/23
Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Codeine
Trade Name Paveral
Indication Management of pain, diarrhea, cough suppressant
Action Binds to opiate receptors in the CNS and alters perception of pain while producing a general depression of the CNS. This depression also causes a decrease in the cough reflex and GI motility.
Therapeutic Class Allergy, cold, cough remedy, antitussive, opioid analgesic
Pharmacologic Class Opioid...
Published 05/15/23
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Generic Name Clopidogrel
Trade Name Plavix
Indication Atherosclerotic events, MI, CVA, PVD, acute coronary syndrome
Action Inhibits platelet aggregation
Therapeutic Class Antiplatelet agent
Pharmacologic Class Platelet aggregation inhibitors
Nursing Considerations • May cause GI bleeding, neutropenia, hypercholesterolemia
• May increase risk for bleeding in warfarin, aspirin, heparin
• Can increase...
Published 05/12/23
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Generic Name Clindamycin
Trade Name Cleocin
Indication Skin infections, respiratory tract infections, septicemia, intra-abdominal infections,
osteomyelitis
Action Bacteriostatic: inhibits protein synthesis
Therapeutic Class Anti-infectives
Pharmacologic Class Lincosamide
Nursing Considerations • Arrhythmias, pseudomembranous colitis, diarrhea, phlebitis
• Monitor bowel function
• Assess for...
Published 05/10/23
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Generic Name Ciprofloxacin
Trade Name Cipro
Indication Urinary tract infections, gonorrhea, respiratory tract infections, bronchitis,
pneumonia, skin and bone infections, infectious diarrhea, abdominal infections
Action Inhibits bacterial DNA synthesis
Therapeutic Class Anti-infectives
Pharmacologic Class Fluoroquinolone
Nursing Considerations • Contraindicated in allergies
• May cause QT...
Published 05/08/23
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Generic Name Cimetidine
Trade Name Tagamet
Indication Treatment of duodenal ulcers, GERD, heartburn, Zollinger Ellison syndrome,
prevention of GI bleeding in critical patients.
Action Inhibits action of histamine leading to inhibition of gastric acid secretion
Therapeutic Class Antiulcer agent
Pharmacologic Class Histamine H2 antagonist
Nursing Considerations • Increases serum level of warfarin
• Can...
Published 05/05/23