Dr Morgan Langille, an expert in bioinformatics, talks about developing novel technologies and techniques that enable a better understanding of human-microbial interactions.    Dr Langille discusses advances in the microbiome field as well as combining computer science and microbiology to lead to new therapeutics and diagnostics.   Episode Time Stamps 00:00 Intro 00:30, How Dr Langille got into the field of the microbiome 04:30, Gene duplication and reverse transcription 05:48, What is bioinformatics? 06:34, The evolution of bioinformatics  09:30, Genomic islands 1:04 - Phages 14:30 Dr Langille’s first bioinformatics tool  16:00 Bacterial genome libraries  18:20 Extremeophilic bacteria 19:00 Will there be bugs in space 21:42 Bacteria on Mars  22:15 Human microbiome diversity  23:30 Number of human cells vs microbes in the body  25:00 Genomic diversity within the microbiome  28:00 Perfect bioinformatics  33:40 Bioinformatics and microbiome research 34:37 Short read vs long read sequencing  45:30 Shotgun metagenomics  48:00 Bioinformatic tool development  1:01:00 Differences in bioinformatic tools and impact on research  1:06:00 Solutions to current technology challenges in bioinformatics 1:10:06 Tools that Morgan has developed  1:08:05 PICRUSt - bioinformatic tool  1:18:35 Jarvis - bioinformatic tool  1:24:00 Talent wars for bioinformatics  1:26:36 Machine learning and AI 1:32:51 Colorectal cancer and AI  1:36:35 Is blood sterile? 1:38:00 What does the future of medicine look like  1:40:51 DIY FMT